Marguerite Casey was born in Seattle, Washington on September 5, 1900, the only daughter and last of four children to Henry J. and Annie E. Casey. Like her brother Jim, the founder of United Parcel Service, Marguerite Casey believed deeply in the importance of family, and spent much of her adult life working to create opportunities for families and communities to succeed and thrive.

In 1948 Marguerite and her three brothers established the Annie E. Casey Foundation, honoring their mother's legacy by encouraging public policies, human service reforms, and community supports to meet the needs of vulnerable children, youth and families. Over time, the family's desire to serve in this capacity continued to grow. And almost two decades later, Jim Casey's interest in long-term foster care led him to establish Casey Family Programs (1966) in the family's home town of Seattle. Sharing her brother's passion and vision for improving the foster care system, Marguerite served as a board member for Casey Family Programs from 1966-1971. She was also a loyal benefactress of Seattle University, and is remembered fondly for the Christmas tree she provided in Waterfall Garden for the enjoyment of the citizens of Seattle each year.

Marguerite Casey's lifelong generosity made a tremendous difference for thousands of children and families across the United States, and her giving spirit continues to shine today. Marguerite Casey Foundation was officially created by Casey Family Programs in October of 2001 to help expand Casey's outreach and further enhance its near 40-year record of leadership in child welfare. Through the Foundation's work, the memory of Marguerite Casey will endure and serve additional generations yet to come.